Go beyond routine care1 More info with genetic insights for Alzheimer’s.

Learn if you have an increased risk based on your genetics.

Original Price: $199 Sale Price: $79
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1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869889/

Health plus Ancestry Service
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Original Price: $199 Sale Price: $79
Add to cart-health

Understanding the facts
about Alzheimer’s.

  • It’s more common than you might think.
    #1
    Alzheimer’s is the #1 cause of
    dementia.2 More info
  • Early action can lead to a healthier you.
    Up
    to     40%
    of dementia cases may be
    preventable.3 More info
  • Make more informed decisions about your care.
    ~1 in 4
    people have the APOE e4 variant — increasing their risk for Alzheimer’s.4 More info

Why genetic testing matters for Alzheimer’s awareness.

Late-Onset Alzheimer’s Disease. You do not have the ε4 variant we tested.
  • Alzheimer’s begins 10-20 years or more before memory loss develops.5 More info Genetic testing can help you identify hidden risks.
  • Strides have been made for Alzheimer’s and its risk factors, many of which are preventable if acted on early.6 More info

Make an informed choice.

You can choose to opt in to our FDA Authorized late-onset Alzheimer’s Genetic Health Risk report. We provide you with information you need to make the right choice for you.

For those at risk, we provide recommendations and emerging science on how you can work to lower Alzheimer’s disease risk.

A sample Late-Onset Alzheimer's Disease report. Your result: You do not have the variant we tested. 0 variants detected in the APOE gene.

Genetic information for Alzheimer’s disease and other neurological conditions:

Included in Health + Ancestry Service.

Find out what else you can learn from your DNA.

Check out the other genetic health reports included in our Health + Ancestry Service.

  • Ancestry Detail Reports (48 reports)

    Population-specific reports with maps covering 3500+ regions, offering a granular view of your ancestry, plus immersive educational content.

    Reports included:
    Americas (Caribbean, Mexico & Central America, Indigenous American, South America);
    East Asia (Chinese, Chinese Dai, Filipino & Austronesian, Indonesian, Thai, Khmer & Myanma, Japanese, Korean, Manchurian & Mongolian, Siberian, Vietnamese);
    Europe (Ashkenazi Jewish, British & Irish, Eastern European, Finnish, French & German, Greek & Balkan, Italian, Sardinian, Scandinavian, Spanish & Portuguese);
    Oceania (Melanesian);
    Central & South Asia (Bengali & Northeast Indian, Central Asian, Gujarati Patidar, Malayali Subgroup, Northern Indian & Pakistani, Southern Indian & Sri Lankan, Southern Indian Subgroup);
    Sub-Saharan Africa (African Hunter-Gatherer, Angolan & Congolese, Ethiopian & Eritrean, Ghanaian, Liberian & Sierra Leonean, Nigerian, Senegambian & Guinean, Somali, Southern East African, Sudanese);
    Western Asia & North Africa (Anatolian, Coptic Egyptian, Cypriot, Egyptian, Iranian, Caucasian & Mesopotamian, Levantine, North African, Peninsular Arab)

  • Family Tree
  • Maternal Haplogroup
  • Paternal Haplogroup
  • Neanderthal Ancestry
  • Ability to Match Musical Pitch
  • Asparagus Odor Detection
  • Back Hair (available for men only)
  • Bald Spot (available for men only)
  • Bitter Taste
  • Bunions
  • Cheek Dimples
  • Cilantro Taste Aversion
  • Cleft Chin
  • Dandruff
  • Earlobe Type
  • Early Hair Loss (available for men only)
  • Earwax Type
  • Eye Color
  • Fear of Heights
  • Fear of Public Speaking
  • Finger Length Ratio
  • Flat Feet
  • Freckles
  • Hair Photobleaching (hair lightening from the sun)
  • Hair Texture
  • Hair Thickness
  • Ice Cream Flavor Preference
  • Light or Dark Hair
  • Misophonia (hatred of the sound of chewing)
  • Mosquito Bite Frequency
  • Motion Sickness
  • Newborn Hair
  • Photic Sneeze Reflex
  • Red Hair
  • Skin Pigmentation
  • Stretch Marks
  • Sweet vs. Salty
  • Toe Length Ratio
  • Unibrow
  • Wake-Up Time
  • Widow's Peak
  • Type 2 Diabetes (Powered by 23andMe Research)
    Genetic likelihood for a disorder of blood sugar regulation
    1,000+ variants in many genes; variants found in many ethnicities
    Learn more
  • Age-Related Macular Degeneration
    Genetic risk for a form of adult-onset vision loss
    2 variants in the ARMS2 and CFH genes; relevant for European descent
  • Alpha-1 Antitrypsin Deficiency
    Genetic risk for lung and liver disease
    2 variants in the SERPINA1 gene; relevant for European descent
  • BRCA1/BRCA2 (Selected Variants)
    Genetic risk based on a limited set of variants for breast, ovarian, prostate and pancreatic cancer
    44 variants in the BRCA1 and BRCA2 genes; most relevant for Ashkenazi Jewish descent; does not include the majority of BRCA1/2 variants found in people of other ethnicities
    Learn more
  • Celiac Disease
    Genetic risk for gluten-related autoimmune disorder
    2 variants near the HLA-DQB1 and HLA-DQA1 genes; relevant for European decent
  • Chronic Kidney Disease (APOL1-Related)
    Genetic risk for a form of chronic kidney disease
    2 variants in the APOL1 gene; relevant for African descent
  • Familial Hypercholesterolemia
    Genetic risk for very high cholesterol, which can increase the risk for heart disease
    24 variants in the LDLR and APOB genes; relevant for European, Lebanese, Old Order Amish descent
  • G6PD Deficiency
    Genetic risk for a form of anemia
    2 variants in the G6PD gene; relevant for African, Southern European, Kurdish Jewish, Middle Eastern, Central Asian, South Asian descent
  • Hereditary Amyloidosis (TTR-Related)
    Genetic risk for a form of nerve and heart damage
    3 variants in the TTR gene; relevant for African American, West African, Portuguese, Brazilian, Northern Swedish, Japanese, Irish, British descent
  • Hereditary Hemochromatosis (HFE‑Related)
    Genetic risk for iron overload
    2 variants in the HFE gene; relevant for European descent
  • Hereditary Thrombophilia
    Genetic risk for harmful blood clots
    2 variants in the F2 and F5 genes; relevant for European descent
  • Late-Onset Alzheimer's Disease
    Genetic risk for a form of dementia
    1 variant in the APOE gene; variant found and studied in many ethnicities
  • MUTYH-Associated Polyposis
    Genetic risk for a specific colorectal cancer syndrome
    2 variants in the MUTYH gene; relevant for Northern European descent
  • Parkinson's Disease
    Genetic risk for a form of movement impairment
    2 variants in the LRRK2 and GBA genes; relevant for European, Ashkenazi Jewish, North African Berber descent
  • ARSACS
    1 variant in the SACS gene; relevant for French Canadian descent
  • Agenesis of the Corpus Callosum with Peripheral Neuropathy
    1 variant in the SLC12A6 gene; relevant for French Canadian descent
  • Autosomal Recessive Polycystic Kidney Disease
    3 variants in the PKHD1 gene
  • Beta Thalassemia and Related Hemoglobinopathies
    10 variants in the HBB gene; relevant for Sardinian, Cypriot, Italian/Sicilian, Greek descent
  • Bloom Syndrome
    1 variant in the BLM gene; relevant for Ashkenazi Jewish descent
  • Canavan Disease
    3 variants in the ASPA gene; relevant for Ashkenazi Jewish descent
  • Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)
    2 variants in the PMM2 gene; relevant for Ashkenazi Jewish, Danish descent
  • Cystic Fibrosis
    29 variants in the CFTR gene; relevant for Ashkenazi Jewish, European, Hispanic/Latino descent
  • D-Bifunctional Protein Deficiency
    2 variants in the HSD17B4 gene
  • Dihydrolipoamide Dehydrogenase Deficiency
    1 variant in the DLD gene; relevant for Ashkenazi Jewish descent
  • Familial Dysautonomia
    1 variant in the ELP1 gene; relevant for Ashkenazi Jewish descent
  • Familial Hyperinsulinism (ABCC8-Related)
    3 variants in the ABCC8 gene; relevant for Ashkenazi Jewish descent
  • Familial Mediterranean Fever
    7 variants in the MEFV gene; relevant for Arab, Armenian, Sephardic Jewish, Turkish descent
  • Fanconi Anemia Group C
    3 variants in the FANCC gene; relevant for Ashkenazi Jewish descent
  • GRACILE Syndrome
    1 variant in the BCS1L gene; relevant for Finnish descent
  • Gaucher Disease Type 1
    3 variants in the GBA (also known as GBA1) gene; relevant for Ashkenazi Jewish descent
  • Glycogen Storage Disease Type Ia
    1 variant in the G6PC gene; relevant for Ashkenazi Jewish descent
  • Glycogen Storage Disease Type Ib
    2 variants in the SLC37A4 gene
  • Hereditary Fructose Intolerance
    4 variants in the ALDOB gene; relevant for European descent
  • Leigh Syndrome, French Canadian Type
    1 variant in the LRPPRC gene; relevant for French Canadian descent
  • Limb-Girdle Muscular Dystrophy Type 2D
    1 variant in the SGCA gene
  • Limb-Girdle Muscular Dystrophy Type 2E
    1 variant in the SGCB gene; relevant for Amish descent
  • Limb-Girdle Muscular Dystrophy Type 2I
    1 variant in the FKRP gene
  • MCAD Deficiency
    4 variants in the ACADM gene; relevant for European descent
  • Maple Syrup Urine Disease Type 1B
    2 variants in the BCKDHB gene; relevant for Ashkenazi Jewish descent
  • Mucolipidosis Type IV
    1 variant in the MCOLN1 gene; relevant for Ashkenazi Jewish descent
  • Neuronal Ceroid Lipofuscinosis (CLN5-Related)
    1 variant in the CLN5 gene; relevant for Finnish descent
  • Neuronal Ceroid Lipofuscinosis (PPT1-Related)
    3 variants in the PPT1 gene; relevant for Finnish descent
  • Niemann-Pick Disease Type A
    3 variants in the SMPD1 gene; relevant for Ashkenazi Jewish descent
  • Nijmegen Breakage Syndrome
    1 variant in the NBN gene
  • Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related)
    8 variants in the GJB2 gene; relevant for many ethnicities, including Ashkenazi Jewish, East/Southeast Asian, European, and Ghanaian descent. May also be relevant for Hispanic/Latino, Northern African/Middle Eastern, and South Asian descent
  • Pendred Syndrome and DFNB4 Hearing Loss (SLC26A4-Related)
    6 variants in the SLC26A4 gene
  • Phenylketonuria and Related Disorders
    23 variants in the PAH gene; relevant for Irish, Northern European descent
  • Pompe Disease
    5 variants in the GAA gene; relevant for African/African American descent; variants also common in European descent
  • Primary Hyperoxaluria Type 2
    1 variant in the GRHPR gene
  • Pyruvate Kinase Deficiency
    1 variant in the PKLR gene
  • Rhizomelic Chondrodysplasia Punctata Type 1
    1 variant in the PEX7 gene
  • Salla Disease
    1 variant in the SLC17A5 gene; relevant for Finnish, Swedish descent
  • Severe Junctional Epidermolysis Bullosa (LAMB3-Related)
    3 variants in the LAMB3 gene
  • Sickle Cell Anemia
    1 variant in the HBB gene; relevant for African, Middle Eastern, South Asian, Caribbean, Mediterranean, Central and South American descent
  • Sjögren-Larsson Syndrome
    1 variant in the ALDH3A2 gene; relevant for Swedish descent
  • Tay-Sachs Disease
    4 variants in the HEXA gene; relevant for Ashkenazi Jewish, Cajun descent
  • Tyrosinemia Type I
    4 variants in the FAH gene; relevant for French Canadian, Finnish descent
  • Usher Syndrome Type 1F
    1 variant in the PCDH15 gene; relevant for Ashkenazi Jewish descent
  • Usher Syndrome Type 3A
    1 variant in the CLRN1 gene; relevant for Ashkenazi Jewish descent
  • Zellweger Spectrum Disorder (PEX1-Related)
    1 variant in the PEX1 gene
  • Alcohol Flush Reaction
  • Caffeine Consumption
  • Deep Sleep
  • Genetic Weight
  • Lactose Intolerance
  • Muscle Composition
  • Saturated Fat and Weight
  • Sleep Movement

Let’s learn more, together.

Add to cartImportant test info

Frequently asked questions

What health conditions does 23andMe test for?
23andMe offers a variety of health reports like Type 2 Diabetes (Powered by 23andMe Research), Celiac Disease Genetic Health Risk Report*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks, BRCA1/BRCA2 (Selected Variants) Genetic Health Risk Report*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks and many more. to see a list of all the reports offered.
What will 23andMe’s Health + Ancestry Service tell me?
Your 23andMe Health reports can tell you how your DNA can impact your chances of developing certain conditions. Wellness reports can help you discover what your DNA has to say about lifestyle factors like diet, exercise, and sleep. And if you’re thinking of starting a family, our Carrier Status reports can tell you if you’re a carrier for genetic variants linked to certain inherited health conditions.*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks
Is 23andMe diagnostic?
No, 23andMe reports do not diagnose any health conditions or provide medical advice. While having a particular genetic variant can be linked to a higher risk for a condition, it does not necessarily mean you will develop the condition. It is also important to remember that these reports do not cover all possible genetic variants that could influence risk. Other non-genetic factors, such as environment and lifestyle, can also influence risk for these conditions. We recommend that you consult with a healthcare professional if a condition runs in your family, you think you might have the condition or you have questions about any genetic or non-genetic risk factors you may have.

2 Headline: Alzheimer’s Disease Fact Sheet
Link: https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet
Source: National Institute on Aging

3 Headline: Dementia Risk Reduction
Link: https://www.cdc.gov/alzheimers-dementia/prevention/?CDC_AAref_Val=https://www.cdc.gov/aging/publications/features/dementia-risk-reduction-june-2022/index.html
Source: Centers For Disease Control and Prevention

4 Headline: Alzheimer’s Disease Genetics Fact Sheet
Link: https://www.nia.nih.gov/health/genetics-and-family-history/alzheimers-disease-genetics-fact-sheet
Source: National Institute on Aging

5 Headline: Changes in Brain Function Occur Years before the Onset of Cognitive Impairment
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828456/
Source: National Library of Medicine

6 Headline: Modifiable Risk Factors for Alzheimer Disease and Related Dementias Among Adults Aged ≥45 Years — United States, 2019
Link: https://www.cdc.gov/mmwr/volumes/71/wr/mm7120a2.htm#:~:text=The%20most%20common%20modifiable%20risk,and%20binge%20drinking%20(10.3%25)
Source: Centers For Disease Control and Prevention

*The 23andMe PGS test includes health predisposition and carrier status reports. Health predisposition reports include both reports that meet FDA requirements for genetic health risks and PRS reports which are based on a genetic model that includes data and insights from 23andMe consented research participants, and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. Each PRS report describes if a person has a certain likelihood of developing a condition, but does not describe a person’s overall likelihood. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future, the health of your fetus, or your newborn child's risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. Warnings & Limitations: The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of 44 variants in the BRCA1 and BRCA2 genes. The report describes if a person's genetic result is associated with an increased risk of developing breast cancer and ovarian cancer and may be associated with an increased risk for prostate cancer, pancreatic cancer, and potentially other cancers. The variants included in this report do not represent the majority of the BRCA1/BRCA2 variants in people of most ethnicities. The MUTYH-Associated Polyposis Genetic Health Risk Report is indicated for reporting the Y179C and G396D variants in the MUTYH gene and an increased risk for colorectal cancer. The two variants included in this report are most common in people of Northern European descent. The Hereditary Prostate Cancer (HOXB13-Related) Genetic Health Risk report is indicated for reporting the G84E variant in the HOXB13 gene. The report describes if a person has the G84E variant and if a male is at increased risk for prostate cancer. The variant included in this report is most common in people of European descent, especially in people of Northern European descent. These reports do not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. These reports are for over-the-counter use by adults, and provide genetic information to inform discussions with a healthcare professional. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. For important information and limitations regarding genetic health risk reports, visit 23andme.com/test-info/.